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Estrogen therapy may be risky for stroke victims 


By: Thomas H. Maugh II 
Los Angeles Times, October 29, 2001 

 

The study follows recent reports that hormone treatment also is not effective in preventing heart disease.

Based on those studies, the American Heart Assn. in July recommended against prescribing the hormone solely to prevent heart disease and strokes. Estrogen therapy is effective, however, at preventing bone loss and easing symptoms of menopause.

Dr. Catherine M. Viscoli and her colleagues at Yale University studied 991 women, with an average age of 71, who had suffered either full strokes or so-called mini-strokes.

The women were randomly assigned to receive either a standard dose of estrogen or a placebo. The team reported in the Oct. 25 New England Journal of Medicine that, after eight years, 99 of the women getting estrogen had suffered further strokes, compared with 93 of those receiving placebo.