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The World Health Organization estimates that by the year 2025, we will be a planet of 8 billion residents. At that time, the number of people age 65 and older will reach 800 million one of every ten persons. We will also enjoy, worldwide, an average life expectancy of 73 years. In order to avert the financially, socially, and medically burdensome task of caring for the swelling aged population, rapid adoption of safe and effective diagnostic and treatment processes that can improve the quality of life in these extended years is a critical imperative to maintain the well-being of society in the twenty second century.. In 1993,a dozen pioneering physicians and scientists met to create the medical specialty of anti-aging medicine. To accomplish a campaign of education and advocacy to advance the acceptance of anti-aging medicine around the globe, we formed the American Academy of Anti-Aging Medicine. As the academy founder, I present to you the original, official definition of anti-aging medicine: Anti-aging medicine is a medical specialty founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age related dysfunction, disorders, and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, anti-aging medicine is based on principles of sound and responsible medical care that are consistent with those applied in other preventive health specialties. Anti-aging medicine has matured into a prestigious medical field that has become recognized by independent public policy organizations. In 2001,the World Future Society -a nonprofit educational and scientific organization founded in 1966 as a neutral clearinghouse exploring the impact of social and technological developments on the future -heralded anti-aging medicine as an effective solution to the growing aging population worldwide (Wagner,2001).The World Future Society notes that "geriatrics may ...be suffering from competition arising in a new health-care subspecialty: anti-aging. "Citing an "aging baby-boom generation [that ]is bringing a potential medical crisis to the fore and a critical lack of doctors who specialize in treating elderly patients," the World Future Society refers to anti-aging medicine as a potential answer, embracing "a realignment of priorities from the problems of the elderly to the opportunities of longer lives "(Wagner,2001).The society also notes that the number of members of the American Academy of Anti-Aging Medicine and certified anti-aging physicians and health practitioners is rising steadily, while the number of certified geriatricians is on the decline. Similarly, the highly respected Global Aging Initiative of the Center for Strategic and International Studies (2001) proclaimed its support of anti-aging medicine in its "Summary Report of the Co-chairmen and Findings and Recommendations of the CSIS Commission on Global Aging." Among the report 's conclusions were that governments should "pursue an integrated strategy designed to raise productivity by ... providing financial support, and creating a favor able tax and regulatory environment for research and development in the new services and health sectors, including disease prevention, anti-aging medicine, and other innovative technology." Indeed, the utilization of advanced medical
technologies is a cornerstone of anti-aging medicine. The American Academy
of Anti-Aging Medicine offers a hopeful and attainable model for medicine
in the new millennium founded on the dramatic advancements offered by the
biotech revolution. The model identifies a continued and expanding arena
of discovery and advancement in our understanding of ways to mitigate
age-related disability and disease and is based on what the academy calls
"techno demography." As conceived by the organization, techno
demography is the application of modern biotechnology to the issues of
diagnosis, prevention, and intervention in aging, such that one may
extrapolate future progress in human aging based on the application of
innovative medical interventions. The model incorporates the impact that
five key areas in biomedical technology can be expected to exert on gains
in Genetic engineering, including work with stem cells. Advancements would allow scientists to alter genetic make-up to eradicate disease and would permit development of a supply source for human cells, tissues, and organs for use in acute emergency care as well as treatment of chronic, debilitating disease. Cloning. This technique holds tremendous promise in producing consistent sources of organs, tissues, and proteins for biomedical use and transplantation in humans. "Nanotechnology. "This form of technology would enable scientists to use tiny tools to manipulate human biology at its most basic levels. Artificial organs. Advancement in this
area Nerve impulse continuity (brain and spinal cord). Progress in this
area would allow nerve signal transmission to be maintained without Recently, ardent critics have actually begun to
gravitate toward adoption of anti-aging medicine first, by renaming it so
that the concept appears to be their original creation. Longevity
medicine, successful aging, healthy aging, optimal aging, and aging
gracefully, among other synonyms, are being substituted by conventional
gerontologists for the term anti-aging. The medical premise of these
alternative terms incorporating "all means that would extend healthy In its continued effort to absorb what it can not deny, the gerontological establishment has expressed a number of conclusions about anti-aging medicine that are presented below, along with a response to each that represents the position of the American Academy of Anti-Aging Medicine: "Some people may prefer to trivialize
'anti-aging,' but it has been a very important part of "Anti-aging 'medicine could be simply defined as
any intervention that delays the development of age-dependent pathology
and other adverse age-related changes that are not officially listed as
diseases "(International Longevity Center-USA,2001). "Further extension [of human life expectancy
]will almost certainly require biomedical intervention to delay
age-related pathology and disease....Clearly, modern technology has made
great strides toward improving human health and enabling greater numbers
of people to survive into old age "(International Longevity
Center-usa,2001). All diseases fall into three categories. The first two -inherited genetic disease and infectious disease -account for only 10 percent of the cost for treating all disease in America. Ninety per cent of all healthcare dollars are spent n extra-ordinary care in the last two t three years of life. Indeed, the leading causes of death have undergone a profound shift. Because of improvements in sanitation and infection control since the turn of the twentieth century, Americans are now losing their health and lives to heart disease (31.4 percent),cancer (23.3 percent),and stroke (6.9 percent)(U.S. Department of Health and Human Services,2000).These three diseases, known collectively as the degenerative diseases of aging, swallow 50 percent of the U.S. health care budget (Health Care Finance Administration,1996).One hundred million Americans are currently being treated for one or another degenerative disease at a healthcare cost of more than $700 billion per year. If we really want to make an impact on healthcare in this country and in the world, we must focus on the degenerative diseases of aging. If we can slow aging, we can eliminate more than 50 percent of all diseases overnight. We can alter this dreadful course by preventing, delaying, or reversing the diseases associated with aging. Anti-aging medicine the application of any therapy or modality that delivers very early detection, prevention, treatment, or reversal of aging related dysfunction and disease, thus enhancing the quality and extending the length of the human lifespan -is the most important new model for healthcare for this new millennium. Anti-aging medicine is the following: It is scientific. Anti-aging diagnostic and treatment practices are supported by scientific evidence and therefore cannot be branded as anecdotal. It is evidence-based Anti-aging medicine is based on an orderly process for acquiring data in order to formulate a scientific and objective assessment upon which effective treatment is assigned Is well-documented by peer-reviewed journals such as Aging, American Journal of Cardiology, Journal of the American Geriatrics Society , and Journal of the American Medical Association , among many others. The benefits of anti-aging medicine are resounding
and clear. As a global population, we are experiencing leaps in life
expectancy, decreases in death rates from the leading causes of death
(heart disease, cancer, and stroke),and, in the United States, we are
seeing a decrease in the use of nursing home care. Most important,
accessibility to quality medical care is improving (U.S. Federal
Interagency Forum on Aging Related Statistics,2000).Clearly, anti- As the German physicist and Nobel Laureate Max Planck (1959)once remarked," An important scientific innovation rarely makes its way by gradually winning over and converting its opponents....Its opponents gradually die out and the growing generation is familiar with the idea from the beginning." It is gratifying that, in the ninth year since its
formal beginnings, anti-aging medicine is gaining recognition from the
gerontological establishment. For 2002,the proponents of anti-aging
medicine -physicians, health professionals, scientists, and academics -are
hopeful that we will continue to close the philosophical gap between us
and our gerontology colleagues. Our goal is to create widespread adoption
of an innovative model of healthcare that demonstrates near term potential
to elevate the quality of life, and extend the length of life, for all. REFERENCES
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