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  Trapped in Their Bodies by Parkinson's


By: John Langone
New York Times, February 12, 200
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Shaking Up Parkinson Disease," by Dr. Abraham Lieberman, Jones & Bartlett Publishers, $18.95.

The opening to this instructive book captures the slowly progressive affliction of Parkinson's disease, which has been called "a disease of moving" and which also affects emotions, thinking and communicating.

"Each day, every day," the author writes, "people with Parkinson disease awaken, trapped in their bodies. They move slowly, their limbs are stiff, their hands shake, and their legs won't do what they want them to. They shuffle instead of taking long strides, and periodically `freeze,' unable to move."

Often beginning with an episodic tremor of a hand, Parkinson's disease may be accompanied by other symptoms, like small cramped handwriting, decreased facial expression, lowered voice volume and feelings of anxiety.

About 1.2 million people in the United States and Canada suffer from Parkinson's, the author estimates, with 60,000 new cases diagnosed each year. No preventive practices or cures have been found, and the cause remains a mystery, although questions have long been raised about the roles, if any, of environmental chemicals, viruses, trauma, drugs and heredity.

A neurologist and the medical director of the National Parkinson Foundation, the author, Dr. Lieberman, sorts through the possible causes. And, he offers patients and the people who treat them advice on maintaining quality of life and assesses drug treatments and surgery.

The operations can destroy altered regions of the brain, clear away abnormal electrical "static" with electrode implants and can sometimes repair damage with transplants of dopamine-producing cells (the decrease of the brain chemical dopamine can produce one or more of the classic signs of the disease).

"People with P.D. and their families must understand it," Dr. Lieberman summarizes, "and approach it unlike anything they've faced in their life."

 


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