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Treating Elderly Flu Sufferers Worth the Cost

 Reuters Health, September 1, 2003

 

NEW YORK (Reuters Health) - Treating people in their 60s and 70s who have the flu with anti-flu drugs is worth the cost, but preventing flu with an annual flu shot is a better strategy, according to a report released Monday

Researchers know that treating younger adults with anti-flu drugs is worthwhile from an economic angle because it cuts time off the job, but until now it was not known whether treating elderly flu sufferers would be worth it.

Dr. Michael B. Rothberg of Baystate Medical Center in Springfield, Massachusetts, and colleagues used published information and computer models to compare the costs of a variety of strategies for dealing with flu in the young and old.

As they report in the Annals of Internal Medicine, they found that it is cost-effective to treat people older than age 65 who had not been vaccinated or who were at high risk for complications due to flu with the anti-flu drug oseltamivir (Tamiflu) without first testing for flu.

For vaccinated or low-risk patients, it's best to test for flu first and then treat with oseltamivir if the test is positive, according to the researchers.

Oseltamivir has fewer side effects than amantadine, another drug used to treat flu, and is effective against both type A and type B influenza. However, amantadine is a cost- effective alternative for people who have no prescription drug benefits, they say.

Frail elderly individuals should avoid amantadine, especially if they have heart failure or kidney problems, the researchers say. They also say that rimantadine, another treatment for flu, is not cost-effective under any circumstances, largely because it is less effective than the other agents.

The team emphasizes that annual flu shots are the most cost-effective strategy, and that anti-flu drugs only work if they are started within 48 hours of the start of flu symptoms.

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