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Older Patients Benefit from Statin Use-Study


Reuters, November 18, 2002

 

CHICAGO - Elderly patients who use cholesterol-lowering drugs may enjoy the same benefits as their younger counterparts, researchers reported on Monday, based on results of a landmark trial.

Researchers found a 15 percent combined reduction in the risk of heart attack and stroke among a group of patients over the age of 70, but most of that benefit came from the reduction of heart attack risk.

The three-year trial involved 5,804 patients aged 70 to 82 in three European centers, including 3,239 patients with blood vessel disease and 2,565 patients who were at high risk of contracting the disease because of smoking, high blood pressure and diabetes.

Patients were given Bristol-Myers Squibb Co.'s pravastatin, sold under the name of Pravachol, which lowers cholesterol by blocking the enzyme that makes it. It found that pravastatin, a member of the "statin" class of drugs, significantly reduces coronary events by 19 percent and deaths linked with coronary events by 24 percent.

The study, presented at a meeting of the American Heart Association, provided the first scientific evidence of the effectiveness of such drugs in treating heart disease in older patients.


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