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New Zealand: Elderly at Risk as B12 Runs Short

By Janine Rankin, Stuff.co.nz

 

 May 23, 2003

New Zealand - The vitamin, marketed as Neo Cytamen, is used mainly to treat pernicious anaemia and vitamin deficiency in elderly patients, says Palmerston North pharmacist Glen Caves.

Mr Caves said he had to lend a box if the injectable vitamin to the Palmerston North Hospital pharmacy the other day, but now almost everyone had run out.

Pernicious anaemia is an auto-immune disease that interferes with the body's ability to absorb vitamin B12. Inadequate amounts of the vitamin restrict the blood's oxygen-carrying capacity. It affects patients' nerves, causing numbness and tingling, a shortness of breath and a feeling of lethargy.

Under normal supply conditions, it is easily corrected with injections of vitamin B12. Many patients return to normal after an intensive course, while others need ongoing therapy.

"Some elderly people could go downhill without it. They may feel very, very weak."

Mr Caves said prescribed dosages seemed to have increased.

Supplier GlaxoSmithKline corporate communications head Ron Murray said the New Zealand demand used to be for about 4000 units a month, but that demand had "grown amazingly" in recent months for reasons he didn't understand.

"We've been caught out a little."

He said it hadn't been easy for Australian manufacturers to suddenly gear up to meet the high demand.

Mr Murray said the company didn't keep high stocks, but had a small supply on stand-by for emergency situations. There is no alternative to the product.

A fresh supply of 15,000 units was expected in New Zealand next week. That would last for about two months at current demand levels.

Mr Caves said he was concerned there would be increasing numbers of drug outages unless there were improvements in the way drugs were ordered.

He said in another recent example pharmacists ran out of glicazide, a drug used particularly among elderly people to manage blood sugar levels in non-insulin dependent diabetes.

There was a problem with one batch, and without any stocks in reserve, the supplier had sourced an alternative, "that we think is all right", Mr Caves said.

"There are a lot of reasons for outages, and just-in-time ordering is a key.

"Nobody makes enough to be able to afford to hold vast stocks. We lose money on some of these medicines, so we are not going to hold any more than we have to.

"The wholesalers make their standard small margin and like to be efficient with turnover."

Drug buying agency Pharmac chief executive Wayne McNee said he was aware of the supply shortage, but there was nothing Pharmac had done that would have influenced the situation.


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